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Artículo
Aquaporin-4 expression switches from white to gray matter regions during postnatal development of the central nervous system
Mayo Leon, Francisco; Gonzalez Vinceiro, Lourdes; Hiraldo González, Laura; Calle-Castillejo, Claudia; Morales-Álvarez, Sara; Ramírez Lorca, Reposo; Echevarría Irusta, Miriam (MDPI, 2023-02-03)Aquaporin-4 (AQP4) is the most abundant water channel in the central nervous system and plays a fundamental role in ...
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Artículo
Cellular distribution of brain aquaporins and their contribution to cerebrospinal fluid homeostasis and hydrocephalus
Trillo Contreras, José Luis; Ramírez Lorca, Reposo; Villadiego Luque, Francisco Javier; Echevarría Irusta, Miriam (MDPI, 2022)Brain aquaporins facilitate the movement of water between the four water compartments: blood, cerebrospinal fluid, ...
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Artículo
Combined effects of aquaporin-4 and hypoxia produce age-related hydrocephalus
Trillo Contreras, José Luis; Ramírez Lorca, Reposo; Hiraldo González, Laura; Sánchez Gomar, Ismael; Galán-Cobo, Ana; Suárez-Luna, Nela; Sánchez de Rojas de Pedro, Eva; Toledo Aral, Juan José; Villadiego Luque, Francisco Javier; Echevarría Irusta, Miriam (Elsevier, 2018)Aquaporin-4, present in ependymal cells, in glia limiting and abundantly in pericapillary astrocyte foot pro cesses, and ...
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Artículo
Comparative analysis for the presence of IgG anti-aquaporin-1 in patients with NMO-Spectrum disorders
Sánchez Gomar, Ismael; Díaz Sánchez, María; Uclés Sánchez, Antonio José; Casado Chocán, José Luis; Suárez-Luna, Nela; Ramírez Lorca, Reposo; Villadiego Luque, Francisco Javier; Toledo Aral, Juan José; Echevarría Irusta, Miriam (MDPI AG, 2016-07-23)Detection of IgG anti-Aquaporin-4 (AQP4) in serum of patients with Neuromyelitis optica syndrome disorders (NMOSD) has ...
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Artículo
Evaluation of aquaporins in the cerebrospinal fluid in patients with idiopathic normal pressure hydrocephalus
Hiraldo González, Laura; Trillo Contreras, José Luis; García Miranda, Pablo; Pineda Sánchez, Rocío; Ramírez Lorca, Reposo; Rodrigo Herrero, Silvia; Olivares Blanco, Magdalena; Oliver, María; Bernal, María; Franco Macías, Emilio; Villadiego Luque, Francisco Javier; Echevarría Irusta, Miriam (PLOS, 2021)Brain aquaporin 1 (AQP1) and AQP4 are involved in cerebrospinal fluid (CSF) homeostasis and might participate in the origin ...
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Artículo
Expression Pattern of Aquaporin 1 and Aquaporin 3 in Melanocytic and Nonmelanocytic Skin Tumors
Osorio, Giovana; Zulueta-Dorado, Teresa; González Rodríguez, Patricia; Bernabéu-Wittel, José; Conejo-Mir Sánchez, Julián; Ramírez Lorca, Reposo; Echevarría Irusta, Miriam (American journal of clinical pathology, 2019)Objectives: Study of aquaporin 1 (AQP1) and aquaporin 3 (AQP3) expression to understand its potential role in the ...
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Artículo
Full protection from SARS-CoV-2 brain infection and damage in susceptible transgenic mice conferred by MVA-CoV2-S vaccine candidate
Villadiego Luque, Francisco Javier; García-Arriaza, Juan; Ramírez Lorca, Reposo; García Swinburn, Roberto; Cabello Rivera, Daniel; Rosales Nieves, Alicia E.; Muñoz Cabello, Ana María; López Barneo, José; Toledo Aral, Juan José (Nature Publishing Group, 2023)Vaccines against SARS-CoV-2 have been shown to be safe and effective but their protective efficacy against infection in ...
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Artículo
Generation of Periventricular Reactive Astrocytes Overexpressing Aquaporin 4 Is Stimulated by Mesenchymal Stem Cell Therapy
García Bonilla, María; Ojeda Pérez, Betsaida; Shumilov, Kirill; Rodríguez-Pérez, Luis Manuel; Vitorica Ferrández, Francisco Javier; Ramírez Lorca, Reposo; Echevarría Irusta, Miriam; Páez González, Patricia; Jiménez, Antonio J. (MDPI AG, 2023-03-15)Aquaporin-4 (AQP4) plays a crucial role in brain water circulation and is considered a therapeutic target in hydrocephalus. ...
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Tesis Doctoral
Implicación de acuaporina-4 en las bases celulares y moleculares del desarrollo postnatal del sistema nervioso central murino
Mayo Leon, Francisco (2023-06-02)El agua es un elemento básico en la fisiología de los seres vivos. A escala celular, su transporte se encuentra facilitado ...
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Artículo
Is Carotid Body Infection Responsible for Silent Hypoxemia in COVID-19 Patients?
Villadiego Luque, Francisco Javier; Ramírez Lorca, Reposo; Cala, Fernando; Labandeira-García, José L.; Esteban, Mariano; Toledo Aral, Juan José; López Barneo, José (Oxford University Press (OUP), 2021) -
Artículo
Methylation alterations are not a major cause of PTTG1 misregulation
Hidalgo Pascual, Manuel; Ruiz Laza, Agustín; Galán Retamal, José Jorge; Japón Rodríguez, Miguel Ángel; Sáez Torres, Carmen; Ramírez Lorca, Reposo; Royo Sánchez-Palencia, José Luis; Castilla Ramírez, Carolina Adoración; Ferrero, Eduardo; Peláez, P. (2008) -
Artículo
Overexpression of AQP3 Modifies the Cell Cycle and the Proliferation Rate of Mammalian Cells in Culture
Galán-Cobo, Ana; Ramírez Lorca, Reposo; Serna, Ana; Echevarría Irusta, Miriam (PUBLIC LIBRARY SCIENCE, 2015-09-14)Abnormal AQP3 overexpression in tumor cells of different origins has been reported and a role for this enhanced AQP3 ...
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Artículo
Predictive Value of Serum Antibodies and Point Mutations of AQP4, AQP1 and MOG in A Cohort of Spanish Patients with Neuromyelitis Optica Spectrum Disorders
García Miranda, Pablo; Morón Civanto, Francisco Jesús; Martínez Olivo, María del Mar; Suárez-Luna, Nela; Ramírez Lorca, Reposo; Lebrato-Hernández, Lucía; Lamas-Pérez, Lucía; Navarro, Gemma; Abril-Jaramillo, Javier; García Sánchez, María Isabel; Casado Chocán, José Luis; Uclés Sánchez, Antonio José; Romera, Mercedes; Echevarría Irusta, Miriam; Díaz Sánchez, María (MDPI, 2019-11-19)The detection of IgG aquaporin-4 antibodies in the serum of patients with Neuromyelitis optica (NMO) has dramatically ...
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Artículo
Role of aquaporins in cell proliferation: What else beyond water permeability?
Galán-Cobo, Ana; Ramírez Lorca, Reposo; Echevarría Irusta, Miriam (Taylor & Francis Open Access, 2016-02-21)In addition to the extensive data demonstrating the importance of mammalian AQPs for the movement of water and some small ...